| Protein Name | C-C chemokine receptor type 8 |
| Gene Name | CCR8 |
| Uniprot | P51685 (Human); P56484 (Mouse) |
| Synonym | CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8; C-C chemokine receptor type 8; CC chemokine receptor 8; CC chemokine receptor CHEMR1 |
| Background | CCR-8, also known as cluster of differentiation w198 (CDw198), GPR-CY6 or CKR-L1, is a member of the beta chemokine receptor family, which is supposed to be a seven transmembrane protein similar to G protein-coupled receptors. It is encoded by CCR8 gene (in human), and primarily expressed in T-helper type-2 lymphocytes and peritoneal macrophages. The ligands of CCR-8 have been identified to be I-309 (CCL1), thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta). |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX468 | NativeExtract™ Human CCR8 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPVLP-049 | MemDX™ Recombinant Human CCR8 Membrane Protein in Virus-Like Particles (MP-VLPs) | HEK293 cells | Full length | VLPs |
| MP1337J | MemDX™ Membrane Protein Human CCR8 (C-C motif chemokine receptor 8) for Antibody Discovery | E.colicell-free | Full length | Detergent |
| S01YF-0423-KX5 | MemDX™ Human CCR8 Membrane Protein in Membrane Nanoparticles (MNP), Full Length | HEK293 cells | Full length | N/A |
| Please for more products or customization | ||||
With our advanced cell line construction platform and extensive experience, we offer you high-quality and highly stable membrane protein stable cell lines to support your research and drug development.
| CAT# | Product Name | Target Species | Protein Length |
| S01YF-0123-KX146 | MemDX™ Human CCR8 HEK293T Cell Line | Human | HEK293T |
| S01YF-0123-KX95 | MemDX™ Mouse CCR8 HEK293T Cell Line | Mouse | HEK293T |
| S01YF-0123-KX48 | MemDX™ Rat CCR8 HEK293T Cell Line | Rat | HEK293T |
| S01YF-0123-KX19 | MemDX™ Human CCR8 MC-38 Cell Line | Human | MC-38 |
| Please contact us for more products or customization | |||
F***st: MemDX™ Recombinant Human CCR8 Membrane Protein in Virus-Like Particles (MP-VLPs)
I recently purchased the Human CCR8 protein from Creative Biolabs and couldn't be more satisfied. The quality of the protein was outstanding. It arrived in perfect condition, and the purity and activity levels were exactly as described on their website. Their customer service was also top-notch.
22/ Oct/2023
I*y: MemDX™ Recombinant Human CCR8 Membrane Protein in Virus-Like Particles (MP-VLPs)
I've had a very positive experience with Creative Biolabs. The technical support team was also very helpful. They provided valuable advice on how to handle and use the protein to get the best results. I'm very pleased with my purchase and will be using Creative Biolabs again in the future.
16/Jun/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers gene function analysis services. Investigate the biological processes, molecular functions, and cellular components associated with CCR8. This helps understand its role as a cell surface receptor involved in immune response, cell adhesion, G protein-coupled receptor signaling pathway, chemokine-mediated signaling pathway, and chemotaxis.
Creative Biolabs offers viral vectors delivery system development services. Utilize viral vectors to deliver genes or therapeutic agents that target CCR8. These vectors can efficiently introduce genetic material into target cells, enabling the expression of CCR8 inhibitors or other therapeutic molecules.
Creative Biolabs can develop nanoparticles as carriers for CCR8-targeting therapies. Nanoparticles can protect the therapeutic agents from degradation, facilitate their delivery to specific tissues or cells, and improve their bioavailability and therapeutic efficacy.
Creative Biolabs offers comprehensive and innovative services to drive the development of CCR8 cell therapy. Please for more services.
Creative Biolabs offers chemotaxis assays services. Perform chemotaxis assays to study the migration of CCR8+ cells towards their natural chemokine agonist, CCL1. This helps understand the role of CCR8 signaling in cell migration and the potential impact of CCR8 antagonists on this process.
Creative Biolabs offers antitumor activity evaluation services. Administer anti-CCR8 antibodies to tumor-bearing mice and examine the antitumor activity both in vivo and in ex vivo confirmative models. Assess the effects on tumor growth, immune cell infiltration, and overall survival to determine the therapeutic potential of CCR8-targeted therapies.
Creative Biolabs offers single-cell RNA-Seq data analysis services. Obtain single-cell RNA-seq data of tumor-infiltrating T cells and analyze the gene expression profiles of CCR8+ and CCR8− Tregs.
With the world's broadest range of knowledge in membrane protein, Creative Biolabs has worked all out in the field of membrane protein preparation to support membrane protein studies, and offers not only regular membrane protein preparation services but also customized services based on the requirements of our clients. Please feel free to for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.