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CCR-8 Membrane Protein Introduction

Introduction Related Products Customer Reviews Customized Production Drug Discovery

Introduction of CCR8

Protein Name C-C chemokine receptor type 8
Gene Name CCR8
Uniprot P51685 (Human); P56484 (Mouse)
Synonym CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8; C-C chemokine receptor type 8; CC chemokine receptor 8; CC chemokine receptor CHEMR1
Background CCR-8, also known as cluster of differentiation w198 (CDw198), GPR-CY6 or CKR-L1, is a member of the beta chemokine receptor family, which is supposed to be a seven transmembrane protein similar to G protein-coupled receptors. It is encoded by CCR8 gene (in human), and primarily expressed in T-helper type-2 lymphocytes and peritoneal macrophages. The ligands of CCR-8 have been identified to be I-309 (CCL1), thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta).

CCR8 Related Products

Membrane Protein Products

Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.

CAT# Product Name Expression System Protein Length Solubilizing Agents
S01YF-1023-KX468 NativeExtract™ Human CCR8 Membrane Protein (Full length, Super Nanodisc) HEK293 cells Full length Native Nanodisc
MPVLP-049 MemDX™ Recombinant Human CCR8 Membrane Protein in Virus-Like Particles (MP-VLPs) HEK293 cells Full length VLPs
MP1337J MemDX™ Membrane Protein Human CCR8 (C-C motif chemokine receptor 8) for Antibody Discovery E.colicell-free Full length Detergent
S01YF-0423-KX5 MemDX™ Human CCR8 Membrane Protein in Membrane Nanoparticles (MNP), Full Length HEK293 cells Full length N/A
Please contact us for more products or customization

Membrane Protein Stable Cell Lines

With our advanced cell line construction platform and extensive experience, we offer you high-quality and highly stable membrane protein stable cell lines to support your research and drug development.

CAT# Product Name Target Species Protein Length
S01YF-0123-KX146 MemDX™ Human CCR8 HEK293T Cell Line Human HEK293T
S01YF-0123-KX95 MemDX™ Mouse CCR8 HEK293T Cell Line Mouse HEK293T
S01YF-0123-KX48 MemDX™ Rat CCR8 HEK293T Cell Line Rat HEK293T
S01YF-0123-KX19 MemDX™ Human CCR8 MC-38 Cell Line Human MC-38
Please contact us for more products or customization

Customer Reviews

F***st: MemDX™ Recombinant Human CCR8 Membrane Protein in Virus-Like Particles (MP-VLPs)

I recently purchased the Human CCR8 protein from Creative Biolabs and couldn't be more satisfied. The quality of the protein was outstanding. It arrived in perfect condition, and the purity and activity levels were exactly as described on their website. Their customer service was also top-notch.

22/ Oct/2023

I*y: MemDX™ Recombinant Human CCR8 Membrane Protein in Virus-Like Particles (MP-VLPs)

I've had a very positive experience with Creative Biolabs. The technical support team was also very helpful. They provided valuable advice on how to handle and use the protein to get the best results. I'm very pleased with my purchase and will be using Creative Biolabs again in the future.

16/Jun/2024

Customized Membrane Protein Production

Different membrane protein formats (Creative Biolabs Original)

CCR8 Drug Discovery and Development

CCR8 Small Molecule Drug Development

Small molecule drug development services (Creative Biolabs Original)

Anti-CCR8 Antibody Discovery

Processes of antibody discovery (Creative Biolabs Original)

CCR8 Gene Therapy Development

We provide tailored solutions to meet your specific requirements. Please inquire us for more services.

Gene Function Analysis

Creative Biolabs offers gene function analysis services. Investigate the biological processes, molecular functions, and cellular components associated with CCR8. This helps understand its role as a cell surface receptor involved in immune response, cell adhesion, G protein-coupled receptor signaling pathway, chemokine-mediated signaling pathway, and chemotaxis.

Viral Vectors Delivery System

Creative Biolabs offers viral vectors delivery system development services. Utilize viral vectors to deliver genes or therapeutic agents that target CCR8. These vectors can efficiently introduce genetic material into target cells, enabling the expression of CCR8 inhibitors or other therapeutic molecules.

Nanoparticle Delivery System

Creative Biolabs can develop nanoparticles as carriers for CCR8-targeting therapies. Nanoparticles can protect the therapeutic agents from degradation, facilitate their delivery to specific tissues or cells, and improve their bioavailability and therapeutic efficacy.

CCR8 Cell Therapy Discovery

Creative Biolabs offers comprehensive and innovative services to drive the development of CCR8 cell therapy. Please inquire with us for more services.

Chemotaxis Assays

Creative Biolabs offers chemotaxis assays services. Perform chemotaxis assays to study the migration of CCR8+ cells towards their natural chemokine agonist, CCL1. This helps understand the role of CCR8 signaling in cell migration and the potential impact of CCR8 antagonists on this process.

Antitumor Activity Evaluation

Creative Biolabs offers antitumor activity evaluation services. Administer anti-CCR8 antibodies to tumor-bearing mice and examine the antitumor activity both in vivo and in ex vivo confirmative models. Assess the effects on tumor growth, immune cell infiltration, and overall survival to determine the therapeutic potential of CCR8-targeted therapies.

Single-Cell RNA-Seq Data Analysis

Creative Biolabs offers single-cell RNA-Seq data analysis services. Obtain single-cell RNA-seq data of tumor-infiltrating T cells and analyze the gene expression profiles of CCR8+ and CCR8− Tregs.

With the world's broadest range of knowledge in membrane protein, Creative Biolabs has worked all out in the field of membrane protein preparation to support membrane protein studies, and offers not only regular membrane protein preparation services but also customized services based on the requirements of our clients. Please feel free to contact us for more details.


All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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