Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsCholecystokinin (CCK) is a peptide gastrointestinal hormone responsible for stimulating the digestion of fat and protein. This CCK peptide hormone exerts its biological functions by interacting with membrane G protein-coupled receptors named Cholecystokinin receptors (CCKRs) located on multiple cellular targets in the central nervous system and peripheral organs. Currently, two types of CCKRs have been identified on a pharmacological basis: CCKAR and CCKBR. CCKARs are predominantly in the peripheral alimentary system and more fundamentally convey digestive tract-mediated CCK satiety signaling, while CCKBRs are predominantly brain receptors which mediate CCK signals that are involved with memory, cognition, anti-analgesia, and anxiety. Studies have reported the implication of these CCK receptors in different human diseases, such as cancers in peripheral organs and different psychiatric disorders.
The variety of physiological functions that can be regulated through the CCK receptors and their potential use as targets for the treatment of several human diseases have stimulated searches for specific, potent agonists and antagonists of these receptors, such as A-71623 and devazepide, respectively. Lots of effort have been made to establish the importance and relevance of these receptors to human physiology and pathophysiology. Here, we give an introduction of these two subtypes of human CCK receptors and the recent publications.
Since the two receptors have been actively studied for their functions and applications, Creative Biolabs now presents our unique Magic™ membrane protein production platform, which provides the most comprehensive membrane protein preparation services for our clients to investigate their target of interest in vitro. To obtain your protein in the functional formats, we offer many reconstitution strategies including detergent micelles, liposomes, nanodiscs, lipoparticles, polymers, etc. With a full understanding of the fact that different formats are applicable for different downstream research purposes, we can customize the services and select the optimal solution for your project.
Additionally, being one of the leading companies for antibody development, Creative Biolabs is proud to provide antibody discovery services against membrane protein targets. Please see Magic™ membrane protein antibody discovery for more information. We also present DNA immunization service for anti-membrane protein antibody development. contact us to discuss your requirements with our professional scientists.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
