ADH-503(Cat#: CTI-012)
This product is a potent CD11b agonist, it can induce the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses.
Summary
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Specifications
| CAS No. |
2055362-74-6 |
| Formula |
C₂₇H₂₈N₂O₅S₂ |
| Molecular Weight |
524.65 |
| SMILES |
O=C([O-])C1=CC=C(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)C=C1.OCC[N+](C)(C)C.[(Z)] |
| Purity |
95% |
| Solubility |
Soluble in DMSO |
| Storage |
Store at -4°C for short term; at -20 °C for long-term storage. |
| Target |
CD11b |
| Introduction |
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). It is involved in the complement system due to its capacity to bind inactivated complement component 3b (iC3b). |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
