Anti-ABCC1 Aptamer(Cat#: CTApt-2390)
This product is an aptamer which binds to the ABCC1 with an affinity of <50 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ABCC1 |
| Alternative Names |
ATP Binding Cassette Subfamily C Member 1; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1; Glutathione-S-Conjugate-Translocating ATPase ABCC1; Multidrug Resistance-Associated Protein 1; Leukotriene C(4) Transporter; LTC4 Transporter; GS-X; MRP1; MRP; ATP-Binding Cassette Transporter Variant ABCC1delta-Ex13&14; ATP-Binding Cassette Transporter Variant ABCC1delta-Ex25&26; ATP-Binding Cassette Transporter Variant ABCC1delta-Ex1; ATP-Binding Cassette Transporter Variant ABCC1delta-Ex25; ATP-Binding Cassette Sub-Family C Member 1; Multidrug Resistance Associated Protein 1; EC 3.6.3.44; EC 7.6.2.; EC 7.6.2.3; EC 3.6.3; ABC29; ABCC1; ABCC |
| Gene ID |
4363 |
| UniProt ID |
P33527 |
| Target Overview |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. |
| Chemical Modification |
RNA |
| Length |
60-80 nt |
| Affinity (Kd) |
<50 nM |
| Binding Conditions/Buffer |
150 mmol/l NaCl, 2 mmol/l CaCl2, 20 mmol/l HEPES (pH 7.4), 0,01% BSA |
| GC Content |
52% |
| Molecular Weight |
19063.0 |
| nmoles/OD260 |
1.502 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
