Anti-ACACB Aptamer SELEX Service(Cat#: CTApt-2448)

Name: Anti-ACACB Aptamer SELEX Service
SKU: CTApt-2448
Rating: 5 (1 reviews)

This is an aptamer development services to screening aptamers binds to the ACACB with an affinity of 1nM~1μM.

Certificate of Analysis Lookup

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Lot Number

Specifications

Target Category	Protein
Target	ACACB
Alternative Names	Acetyl-CoA Carboxylase Beta; Acetyl-CoA Carboxylase 2; ACC2; ACCB; Acetyl-Coenzyme A Carboxylase Beta; ACC-Beta; HACC275; EC 6.4.1.2; ACACB
Gene ID	32
UniProt ID	O00763
Target Overview	Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other