This is an aptamer development services to screening aptamers binds to the ACO2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACO2 |
| Alternative Names | Aconitase 2; Aconitate Hydratase, Mitochondrial; Aconitase 2, Mitochondrial; Mitochondrial Aconitase; Citrate Hydro-Lyase; EC 4.2.1.3; ACONM; Epididymis Secretory Sperm Binding Protein Li 284; HEL-S-284; Aconitase; EC 4.2.1; ICRD; OCA8; OPA9; ACO2 |
| Gene ID | 50 |
| UniProt ID | Q99798 |
| Target Overview | The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |