This is an aptamer development services to screening aptamers binds to the ACOX3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACOX3 |
| Alternative Names | Acyl-CoA Oxidase 3, Pristanoyl; Acyl-Coenzyme A Oxidase 3, Pristanoyl; Peroxisomal Acyl-Coenzyme A Oxidase 3; Branched-Chain Acyl-CoA Oxidase; Pristanoyl-CoA Oxidase; BRCACox; EC 1.3.3.6; ACOX3; BRCOX; PRCOX |
| Gene ID | 8310 |
| UniProt ID | O15254 |
| Target Overview | Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |