Anti-ADAM15 Aptamer(Cat#: CTApt-1004)
This product is an aptamer which binds to the ADAM15 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ADAM15 |
| Alternative Names |
ADAM Metallopeptidase Domain 15; MDC15; Metalloproteinase-Like, Disintegrin-Like, And Cysteine-Rich Protein 15; Disintegrin And Metalloproteinase Domain-Containing Protein 15; A Disintegrin And Metalloproteinase Domain 15 (Metargidin) ; Metalloprotease RGD Disintegrin Protein; Metargidin; MDC-15; EC 3.4.24.- ; EC 3.4.24; ADAM 15; ADAM15 |
| Gene ID |
8751 |
| UniProt ID |
Q13444 |
| Target Overview |
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
