This is an aptamer development services to screening aptamers binds to the ADAM8 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADAM8 |
| Alternative Names | ADAM Metallopeptidase Domain 8; MS2; Disintegrin And Metalloproteinase Domain-Containing Protein 8; A Disintegrin And Metalloproteinase Domain 8; Cell Surface Antigen MS2; CD156; Human Leukocyte Differentiation Antigen; CD156a Antigen; EC 3.4.24.- ; EC 3.4.24; CD156a; CD156A; ADAM 8; ADAM8 |
| Gene ID | 101 |
| UniProt ID | P78325 |
| Target Overview | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |