This is an aptamer development services to screening aptamers binds to the ADH4 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADH4 |
| Alternative Names | Alcohol Dehydrogenase 4 (Class II), Pi Polypeptide; All-Trans-Retinol Dehydrogenase [NAD(+)] ADH4; Alcohol Dehydrogenase Class II Pi Chain; ADH-2; Epididymis Secretory Protein Li 4; Alcohol Dehydrogenase 4; Aldehyde Reductase; HEL-S-4; ADH4 |
| Gene ID | 127 |
| UniProt ID | P08319 |
| Target Overview | This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |