Anti-AGL Aptamer SELEX Service(Cat#: CTApt-2472)

This is an aptamer development services to screening aptamers binds to the AGL with an affinity of 1nM~1μM.

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5’ Modification
 
3’ Modification
 
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Certificate of Analysis Lookup

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Lot Number

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Summary

Specifications
Target Category Protein
Target AGL
Alternative Names Amylo-Alpha-1, 6-Glucosidase, 4-Alpha-Glucanotransferase; Glycogen Debranching Enzyme; Amylo-1, 6-Glucosidase, 4-Alpha-Glucanotransferase; Glycogen Debrancher; GDE; Amylo-Alpha-1, 6-Glucosidase, 4-Alpha-Glucanotransferaseprovided; Glycogen Storage Disease Type III; Glycogen Debranching Protein; AGL
Gene ID 178
UniProt ID P35573
Target Overview This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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