This is an aptamer development services to screening aptamers binds to the AGL with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AGL |
| Alternative Names | Amylo-Alpha-1, 6-Glucosidase, 4-Alpha-Glucanotransferase; Glycogen Debranching Enzyme; Amylo-1, 6-Glucosidase, 4-Alpha-Glucanotransferase; Glycogen Debrancher; GDE; Amylo-Alpha-1, 6-Glucosidase, 4-Alpha-Glucanotransferaseprovided; Glycogen Storage Disease Type III; Glycogen Debranching Protein; AGL |
| Gene ID | 178 |
| UniProt ID | P35573 |
| Target Overview | This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |