Anti-ARAP2 Aptamer SELEX Service(Cat#: CTApt-1317)

This is an aptamer development services to screening aptamers binds to the ARAP2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ARAP2
Alternative Names ArfGAP With RhoGAP Domain, Ankyrin Repeat And PH Domain 2; Arf-GAP With Rho-GAP Domain, ANK Repeat And PH Domain-Containing Protein 2; Centaurin-Delta-1; CENTD1; PARX; Arf And Rho GAP Adapter Protein 2; Centaurin, Delta 1; Protein PARX; KIAA0580; Cnt-D1; ARAP2
Gene ID 116984
UniProt ID Q8WZ64
Target Overview The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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