Anti-ARG2 Aptamer SELEX Service(Cat#: CTApt-2158)

This is an aptamer development services to screening aptamers binds to the ARG2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ARG2
Alternative Names Arginase 2; Arginase-2, Mitochondrial; Kidney-Type Arginase; Non-Hepatic Arginase; Arginase, Type II; Type II Arginase; Arginase II; EC 3.5.3.1; L-Arginine Amidinohydrolas; L-Arginine Ureahydrolase; Nonhepatic Arginase; Kidney Arginase; EC 3.5.3; ARG2
Gene ID 384
UniProt ID P78540
Target Overview Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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