Anti-ARNTL aptamer SELEX Service(Cat#: CTApt-1655)
This is an aptamer development services to screening aptamers binds to the ARNTL with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ARNTL |
| Alternative Names |
Aryl Hydrocarbon Receptor Nuclear Translocator Like; Brain And Muscle ARNT-Like 1; BHLHe5; BMAL1; PASD3; MOP3; Aryl Hydrocarbon Receptor Nuclear Translocator-Like Protein 1; Class E Basic Helix-Loop-Helix Protein 5; Basic Helix-Loop-Helix Family Member E5; Basic-Helix-Loop-Helix-PAS Protein MOP3; PAS Domain-Containing Protein 3; PAS Domain Containing 3; Member Of PAS Protein 3 ; BHLH-PAS Protein JAP3; JAP3; Testis Tissue Sperm-Binding Protein Li 50e; Basic-Helix-Loop-Helix-PAS Orphan MOP3; ARNT-Like Protein 1, Brain And Muscle; Member Of PAS Superfamily 3; BMAL1c; BHLHE5; ARNTL; TIC |
| Gene ID |
406 |
| UniProt ID |
O00327 |
| Target Overview |
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
