This is an aptamer development services to screening aptamers binds to the BAAT with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BAAT |
| Alternative Names | Bile Acid-CoA:Amino Acid N-Acyltransferase; BAT; Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) ; Long-Chain Fatty-Acyl-CoA Hydrolase; Glycine N-Choloyltransferase; Bile Acid-CoA Thioesterase; Choloyl-CoA Hydrolase; BACAT; Bile Acid Coenzyme A: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) ; Bile Acid Coenzyme A:Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) ; EC 2.3.1.65; EC 3.1.2.27; EC 3.1.2.2; BAAT |
| Gene ID | 570 |
| UniProt ID | Q14032 |
| Target Overview | The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |