Anti-BSCL2 aptamer SELEX Service(Cat#: CTApt-1803)

This is an aptamer development services to screening aptamers binds to the BSCL2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BSCL2
Alternative Names BSCL2 Lipid Droplet Biogenesis Associated, Seipin; Seipin; Bernardinelli-Seip Congenital Lipodystrophy Type 2 Protein; Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) ; BSCL2, Seipin Lipid Droplet Biogenesis Associated; Spastic Paraplegia 17 (Silver Syndrome) ; GNG3LG; HMN5C; SPG17; BSCL2; HMN5; PELD
Gene ID 26580
UniProt ID Q96G97
Target Overview This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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