Anti-BuB1 aptamer SELEX Service(Cat#: CTApt-1823)
This is an aptamer development services to screening aptamers binds to the BuB1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BuB1 |
| Alternative Names |
BUB1 Mitotic Checkpoint Serine/Threonine Kinase; BUB1A; HBUB1; Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1; BUB1L; Budding Uninhibited By Benzimidazoles 1 (Yeast Homolog) ; Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) ; BUB1 Budding Uninhibited By Benzimidazoles 1 Homolog; Budding Uninhibited By Benzimidazoles 1 Homolog; Putative Serine/Threonine-Protein Kinase; Mitotic Spindle Checkpoint Kinase; EC 2.7.11.1; BUB1 |
| Gene ID |
699 |
| UniProt ID |
O43683 |
| Target Overview |
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
