This is an aptamer development services to screening aptamers binds to the CXCL13 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | CXCL13 |
| Alternative Names | C-X-C Motif Chemokine Ligand 13; BCA-1; BLC; Small Inducible Cytokine B Subfamily (Cys-X-Cys Motif), Member 13 (B-Cell Chemoattractant) ; B Cell-Attracting Chemokine 1; B Lymphocyte Chemoattractant; Small-Inducible Cytokine B13; C-X-C Motif Chemokine 13; B-Cell Chemoattractant; CXC Chemokine BLC; ANGIE2; SCYB13; ANGIE; BLR1L; BCA1; B-Cell-Homing Chemokine (Ligand For Burkitt'S Lymphoma Receptor-1) ; Chemokine (C-X-C Motif) Ligand 13 (B-Cell Chemoattractant) ; Chemokine (C-X-C Motif) Ligand 13; B-Cell-Attracting Chemokine 1; B-Lymphocyte Chemoattractant; CXCL13; Angie |
| Gene ID | 10563 |
| UniProt ID | O43927 |
| Target Overview | B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |