This product is an aptamer which binds to the ENPEP with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ENPEP |
Alternative Names | Glutamyl Aminopeptidase; Differentiation Antigen Gp160; Aminopeptidase A; EC 3.4.11.7; CD249; Gp160; AP-A; EAP; Glutamyl Aminopeptidase (Aminopeptidase A) ; CD249 Antigen; EC 3.4.11; ENPEP; APA |
Gene ID | 2028 |
UniProt ID | Q07075 |
Target Overview | The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. |
Chemical Modification | DNA/RNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |