Anti-EOGT Aptamer SELEX Service(Cat#: CTApt-1465)

This is an aptamer development services to screening aptamers binds to the EOGT with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target EOGT
Alternative Names EGF Domain Specific O-Linked N-Acetylglucosamine Transferase; AER61; EGF Domain-Specific O-Linked N-Acetylglucosamine (GlcNAc) Transferase; EGF Domain-Specific O-Linked N-Acetylglucosamine Transferase; Extracellular O-Linked N-Acetylglucosamine Transferase; AER61 Glycosyltransferase; C3orf64; EOGT1; Chromosome 3 Open Reading Frame 64; EGF-O-GlcNAc Transferase; EC 2.4.1.255; FLJ33770; AOS4; EOGT
Gene ID 285203
UniProt ID Q5NDL2
Target Overview This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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