Anti-GET3 Aptamer SELEX Service(Cat#: CTApt-2229)

This is an aptamer development services to screening aptamers binds to the GET3 with an affinity of 1nM~1μM.

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Summary
Specifications
Target Category Protein
Target GET3
Alternative Names Guided Entry Of Tail-Anchored Proteins Factor 3, ATPase; TRC40; Transmembrane Domain Recognition Complex 40 KDa ATPase Subunit; ATPase GET3; ARSA-I; ASNA1; ArsA (Bacterial) Arsenite Transporter, ATP-Binding, Homolog 1; ArsA Arsenite Transporter, ATP-Binding, Homolog 1; Transmembrane Domain Recognition Complex, 40kDa; Golgi To ER Traffic 3 Homolog (S. Cerevisiae) ; Golgi To ER Traffic 3 Homolog; Arsenical Pump-Driving ATPase; Arsenite-Stimulated ATPase; EC 3.6.3.16; EC 3.6.-.- ; HARSA-I; HASNA-I; ASNA-I; ARSA1; GET3; ARSA
Gene ID 439
UniProt ID O43681
Target Overview This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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