This is an aptamer development services to screening aptamers binds to the GGT1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | GGT1 |
| Alternative Names | GGT; GTG; GGTD; CD224; GGT 1; D22S672; D22S732 |
| Gene ID | 2678 |
| UniProt ID | P19440 |
| Target Overview | The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |