Anti-Human C5aR1 Aptamer(Cat#: CTMM-0124-RJ18)

This product is an aptamer which binds to Human C5aR1 with an affinity of <50 pM.

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Specifications
Target Category Protein
Target C5aR1
Alternative Names Complement C5a Receptor 1; C5AR; CD88; C5R1; C5A; C5a Anaphylatoxin Chemotactic Receptor; Complement Component 5a Receptor 1; C5a-R; Complement Component 5 Receptor 1 (C5a Ligand); C5a Anaphylatoxin Chemotactic Receptor; C5a Anaphylatoxin Receptor; CD88 Antigen; C5a Ligand; C5aR; C5aR1
Gene ID 728
UniProt ID P21730
Target Overview Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway; mRNA transcription by RNA polymerase II; and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease; asthma; chronic obstructive pulmonary disease; rhinitis; and severe acute respiratory syndrome.
Type RNA
Species Reactivity Human
Length 100-200 nt
Affinity (Kd) <50 pM
Binding Conditions/Buffer 10 mM HEPES, 150 mM NaCl, pH 7.4
GC Content 58.41%
Molecular Weight 34292.7 g/mole
nmoles/OD260 0.807

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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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