This product is a customized aptamer which binds to DC-SIGN with an affinity of 1-50 nM.
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| Target Category | Protein |
| Target | DC-SIGN |
| Alternative Names | Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN1; CD209 Molecule; CD209 Antigen |
| Gene ID | 30835 |
| UniProt ID | Q9NNX6 |
| Target Overview | DC-SIGN, a cell adhesion receptor present on the surface of macrophages and dendritic cells. DC-SIGN also acts as a pathogen recognition receptor. |
| Type | DNA |
| Species Reactivity | Human |
| Length | <50 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | SHCMK containing 20 mM Hepes, 120 mM KCl, 1 mM CaCl₂, and 1 mM MgCl₂, pH 7.35 |
| GC Content | 43% |
| Molecular Weight | 10930.2 g/mole |
| nmoles/OD260 | 2.81 |