Anti-Human MMP14 Aptamer(Cat#: CTMM-0124-JS9)

Name: Anti-Human MMP14 Aptamer
SKU: CTMM-0124-JS9

This product is an aptamer that binds to the Human MMP14 protein with an affinity of <50 nM.

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Specifications

Target Category	Protein
Target	MMP14
Alternative Names	Matrix Metallopeptidase 14; MT1-MMP; Matrix Metallopeptidase 14 (Membrane-Inserted); Membrane-Type-1 Matrix Metalloproteinase; Membrane Type 1 Metalloprotease; Matrix Metalloproteinase-14; EC 3.4.24.80; MT-MMP 1; MMP-14; MMP-X1; MT1MMP; MTMMP1; Matrix Metalloproteinase 14 (Membrane-Inserted); Membrane Type 1-Matrix Metalloproteinase; Membrane-Type Matrix Metalloproteinase 1; EC 3.4.24; MT-MMP; WNCHRS
Gene ID	4323
UniProt ID	P50281
Target Overview	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Type	DNA
Species Reactivity	Human
Length	<50 nt
Affinity (Kd)	<50 nM
Binding Conditions/Buffer	PBS
GC Content	59.76%
Molecular Weight	24759.04 g/mole
nmoles/OD260	1.33

Customer Review

The quality control is evident in every batch we receive

Excellent

Its specificity and affinity for MMP14 have been impressive, showing minimal cross-reactivity in our assays. We've used it in various applications, including ELISA and Western blot, and have consistently seen reliable results.

We've been using this aptamer

Excellent

The data quality has significantly improved since we switched to this product. It binds with high specificity and has proven essential for our experiments analyzing MMP14's role in tumor progression.

Have been thoroughly satisfied

Excellent

We've been particularly impressed with its performance in binding assays and its reliability in detecting MMP14 levels in various tissue samples. The data consistency we get from this aptamer supports its high quality.

A great addition to our research toolkit

Excellent

It binds to MMP14 with high affinity, making it easier to study the protein's structure and function. This aptamer's high quality has been consistent across different experiments.

The aptamer exhibits excellent specificity and stability

Excellent

We've found it to be highly effective in various cell-based assays, including flow cytometry. The reproducibility of results has been outstanding, which speaks volumes about its reliability.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.

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