Anti-Thyroxine Aptamer(Cat#: CTMM-0422-MM20)

This product is an aptamer which binds to the Thyroxine with an affinity of <50 µM.

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3’ Modification
 
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Specifications
Target Category Small Organic
Target Thyroxine
Target Overview Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. It plays vital roles in digestion, heart and muscle function, brain development and maintenance of bones. Thyrotropin-releasing hormone Triiodothyronine Glossary All Hormones Resources for Hormones.
Chemical Modification RNA
Length 40-60 nt
Affinity (Kd) <50 µM
Binding Conditions/Buffer Loading buffer: 10mM Tris-HCl (pH 7.5), 500 mM NaCl, and 1 mM MgCl2.
GC Content 0.6591
Molecular Weight 14313.6 g/mole
Extinction Coefficient 424000 L/(mole·cm)
nmoles/OD260 2.36

Customer Review

An essential tool in our lab
Excellent
Its specificity is impressive, and the results we've obtained have been both reliable and reproducible. We used it in our ELISA assays with excellent results.
Advanced our research on thyroid hormone regulation
Excellent
Its high affinity for thyroxine has enabled us to achieve precise measurements in our experiments. The aptamer's performance has consistently exceeded our expectations, though we found that storing it at the recommended temperature is crucial to maintain its stability.
It has proven invaluable
Excellent
The specificity and low background noise have streamlined our assays. However, it took some optimization to fit it perfectly into our existing protocol, but once that was done, it performed flawlessly.
We use the aptamer for a range of experiments
Excellent
The aptamer's performance has been consistent, and it has provided valuable insights into our research. My only suggestion would be to include more detailed protocols for its use in different types of experiments.
Overall, it's a valuable addition to our toolkit
Excellent
The detection limits are excellent, and it has significantly improved our assay's sensitivity. However, we experienced some challenges with signal intensity in our assays, which required additional troubleshooting.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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