BCX 1470 Methanesulfonate(Cat#: CTI-014)

Name: BCX 1470 Methanesulfonate
SKU: CTI-014
Rating: 5 (1 reviews)

This product is a potent and selective factor D antagonist, it inhibits factor D with the IC50 of 96 nM. It also inhibits C1s with the IC50 of 1.6 nM.

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Specifications

CAS No.	217099-44-0
Formula	C₁₅H₁₄N₂O₅S₃
Molecular Weight	398.48
SMILES	N=C(C1=CC2=CC=C(OC(C3=CC=CS3)=O)C=C2S1)N.O=S(O)(C)=O
IC50	IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin)
Purity	98%
Solubility	DMSO :>33.33 mg/mL (83.64 mM)
Storage	Store at -4°C for short term; at -20 °C for long-term storage.
Target	Factor D
Introduction	The Factor D is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.