This product is an Anti-Human C9 Polyclonal Antiserum from goats immunized with highly purified human C9 protein. It is not a purified IgG fraction.
Host Animal | Goats |
Isotype | IgG |
Immunogen | C8 protein |
Applications | Western Blots; ELISA; Immunodiffusion |
Application Notes | Immunodiffusion: 1/32; WB: 1/64,000; ELISA: 1/128,000 |
Specificity | C8 |
Format | Frozen liquid |
Size | 1ml |
Storage | Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles. |
Target Name | C8 |
Alternative Names | Complement C8; Complement Component C8; Complement Component 8; C8 |
Gene ID | 731 |
UniProt ID | P07357 |
Introduction | C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. C8A inserts into the target membrane, but does not form pores by itself. |