Goat Anti-Human CD46 Polyclonal Antibody(Cat#: CTA-512)
This product is an anti-Human CD46 Polyclonal antibody generated from the Goat. The antibody can be used for WB; ELISA; FC; IHC.
Summary
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Specifications
| Clonality |
Polyclonal |
| Host Animal |
Goat |
| Isotype |
IgG |
| Immunogen |
Mouse myeloma cell line NS0-derived recombinant human CD46
Cys35-Asn328 |
| Species Reactivity |
Human |
| Applications |
WB; ELISA; FC; IHC |
| Application Notes |
WB: 1 µg/mL
FC: 0.25 ug/10^6 cells
IHC: 1-15 µg/mL
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human CD46. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Lyophilized |
| Size |
25; 100 µg |
| Storage |
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
CD46 |
| Alternative Names |
CD46 Molecule; Membrane Cofactor Protein (CD46, Trophoblast-Lymphocyte Cross-Reactive Antigen); Antigen Identified By Monoclonal Antibody TRA-2-10; CD46 Molecule, Complement Regulatory Protein; CD46 Antigen, Complement Regulatory Protein; Trophoblast Leukocyte Common Antigen; MIC10; MCP; TLX; Trophoblast-Lymphocyte Cross-Reactive Antigen; Complement Membrane Cofactor Protein; Trophoblast Leucocyte Common Antigen; Measles Virus Receptor; CD46 Antigen; TRA2.10; AHUS2 |
| Gene ID |
4179 |
| UniProt ID |
P15529 |
Information
| Introduction |
CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. CD46 is an inhibitory complement receptor. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation (through cleavage) of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. The protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
