This product is an Anti-Human Factor I Polyclonal Antiserum from goats immunized with highly purified human Factor I protein. It is not a purified IgG fraction.
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| Host Animal | Goats |
| Isotype | IgG |
| Immunogen | Factor I protein |
| Applications | Western Blots; ELISA; Immunodiffusion |
| Application Notes | Immunodiffusion: 1/8; WB: 1/4,000; ELISA: 1/8,000 |
| Specificity | Factor I |
| Format | Frozen liquid |
| Size | 1ml |
| Storage | Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles. |
| Target Name | Factor I |
| Alternative Names | Konglutinogen-Activating Factor; C3B/C4B Inactivator; C3b-Inactivator; Complement Control Protein Factor I; Complement Factor I Heavy Chain; Light Chain Of Factor I; Complement Component I; I Factor (Complement); EC 3.4.21.45; FI; IF; KAF; AHUS3; ARMD13; C3BINA; C3b-INA |
| Gene ID | 3426 |
| UniProt ID | P05156 |
| Introduction | Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein of the complement system, first isolated in 1966 in guinea pig serum, that regulates complement activation by cleaving cell-bound or fluid phase C3b and C4b. It is a soluble glycoprotein that circulates in human blood at an average concentration of 35 μg/mL. |