Goat Anti-Mouse Clusterin Polyclonal Antibody(Cat#: CTA-419)
This product is an unconjugated anti-Mouse Clusterin Polyclonal antibody generated from the Goat. The antibody can be used for WB; IHC; IP; ELISA.
Summary
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Specifications
| Clonality |
Polyclonal |
| Host Animal |
Goat |
| Isotype |
IgG |
| Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse Clusterin
Glu22-Glu448 |
| Species Reactivity |
Mouse |
| Applications |
WB; IHC; IP; ELISA |
| Application Notes |
WB: 0.1 µg/mL
IHC: 5-15 µg/mL
IP: 25 µg/mL
ELISA (Capture): 0.2-0.8 µg/mL
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Mouse Clusterin. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Lyophilized |
| Size |
25; 100 µg |
| Storage |
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
Clusterin |
| Alternative Names |
Cli; ApoJ; Sgp2; SP-40; Sgp-2; Sugp-2; AI893575; D14Ucla3 |
| Gene ID |
12759 |
| UniProt ID |
Q06890 |
Information
| Introduction |
Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging. CLU is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
