This product is an ELISA kit for the in vitro determination of Human Anti-MBL autoantibody in the samples of Serum, plasma and other biological fluids. It is highly sensitive and available for the detection of Human Anti-MBL autoantibody as low as 2.45 ng/mL.
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Assay Type | Reverse Capture Sandwich ELISA |
Sensitivity | 2.45 ng/mL (6.25-400 ng/mL) |
Species Reactivity | Human |
Target | MBL autoantibody |
Cross Reactivity | No significant cross-reactions have been observed between Human Anti-MBL autoantibody and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | Short-term storage at 4°C and long-term storage at -20°C. |
Introduction | Mannose-binding lectin (MBL) is a lectin that recognizes carbohydrates (D-mannose and L-fucose residues) on the surfaces of pathogens, leading to the activation of complement lectin pathway. Anti-MBL autoantibodies can directly lead to MBL deficiency and complement activity inhibition. Studies indicate that anti-MBL autoantibodies contribute to the development of systemic lupus erythematosus (SLE). |