This product is an ELISA kit for the determination of Human C5b-9 Terminal Complement Complex in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Human C5b-9 Terminal Complement Complex as low as 18.75 pg/mL.
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| Assay Type | Sandwich ELISA |
| Sensitivity | 18.75 pg/mL (31.25-2000 pg/mL) |
| Pack Size | 96 tests |
| Species Reactivity | Human |
| Target | C5b-9 Complex |
| Cross Reactivity | No significant cross-reactions have been observed between Human C5b-9 Terminal Complement Complex and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | The storage of components varies. Please refer to the instructions for details. |
| Introduction | C5b-9 terminal complement complex, also named as membrane attack complex (MAC), is a complex protein composed of the subunits C5b, C6, C7, C8 and several C9 molecules. The MAC is a structure typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is one of the effector proteins of the immune system. The MAC forms transmembrane channels, which disrupt the cell membrane of target cells, leading to cell lysis and death. |
Highly recommend for complement researchExcellentWe used it to measure complement activation in our serum samples, and the results were consistent across multiple assays. The protocol was straightforward, and the kit included all necessary reagents.
This kit is a valuable addition to our immunology toolkitExcellentI was impressed with the human C5b-9 ELISA kit's performance in our lab. It provided reliable and reproducible data, crucial for our inflammation studies. The step-by-step instructions were clear, and the kit components were of high quality.
Highly satisfiedExcellentThe ELISA kit for human C5b-9 was very effective for our experiments. It provided precise measurements and helped us understand the complement activation in our disease models. The kit was easy to use, and the provided standards and controls were helpful in ensuring the accuracy of our results.
Great product overallExcellentThe assay is easy to follow, and the kit components are of high quality. The sensitivity of the kit allowed us to detect low levels of C5b-9, which was crucial for our experiments. Great product!