Human CD59 ELISA Kit-CTK-714(Cat#: CTK-714)
This product is an ELISA kit for the determination of Human CD59 in the samples of Serum, Plasma, Tissue Homogenate, Urine. It is highly sensitive and available for the detection of Human CD59 as low as 0.58 ng/mL.
Summary
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Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
0.58 ng/mL (2.35-150 ng/mL) |
| Pack Size |
96 tests |
| Species Reactivity |
Human |
| Target |
CD59 |
| Cross Reactivity |
No significant cross-reactions have been observed between Human CD59 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
Short-term storage at 4°C and long-term storage at -20°C. |
Information
| Introduction |
CD59 glycoprotein is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
