Human Collectin-11 ELISA Kit(Cat#: CTK-900)
This product is an ELISA kit for the in vitro determination of Human Collectin-11 in the samples of Serum, plasma and other biological fluids. It is highly sensitive and available for the detection of Human Collectin-11 as low as 46.88 pg/mL.
Summary
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Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
46.88 pg/mL (78.13 pg/mL-5000 pg/mL) |
| Species Reactivity |
Human |
| Target |
Collectin-11 |
| Cross Reactivity |
No significant cross-reactions have been observed between Human Collectin-11 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
Short-term storage at 4°C and long-term storage at -20°C. |
Information
| Introduction |
Collectin-11 (CL-11) is a lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
