This product is an ELISA kit for the determination of Human Complement C4BPA in the samples of Serum, plasma and other biological fluids. It is highly sensitive and available for the detection of Human Complement C4BPA as low as 0.38 ng/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 0.38 ng/mL (0.63-40 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Human |
Target | C4BPA |
Cross Reactivity | No significant cross-reactions have been observed between Human Complement C4BPA and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | The storage of components varies. Please refer to the instructions for details. |
Introduction | C4b-binding protein alpha chain controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |