Human Complement iC3b ELISA Kit(Cat#: CTK-920)
This product is an ELISA kit for the in vitro determination of Human iC3b in the samples of Cell Culture Supernatant, Plasma, Serum. It is highly sensitive and available for the detection of Human iC3b as low as 1.88 ng/mL.
Summary
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Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
1.88 ng/mL (3.12-200 ng/mL) |
| Species Reactivity |
Human |
| Target |
iC3b |
| Cross Reactivity |
No significant cross-reactions have been observed between Human iC3b and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
Short-term storage at 4°C and long-term storage at -20°C. |
Information
| Introduction |
Complement iC3b is an inactive form of C3b, which is formed through the cleavage of C3b by factor I in the presence of factor H. Complement receptors on white blood cells are able to bind iC3b, so iC3b functions as an opsonin. Unlike intact C3b, iC3b cannot associate with factor B, thus preventing amplification of the complement cascade through the alternative pathway. Complement factor I can further cleave iC3b into a protein fragment known as C3d. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
