Human Ficolin-1 ELISA Kit(Cat#: CTK-885)
This product is an ELISA kit for the in vitro determination of Human Ficolin-1 in the samples of Cell culture supernatants, serum and plasma (heparin). It is highly sensitive and available for the detection of Human Ficolin-1 as low as 0.02 ng/mL.
Summary
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Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
0.02 ng/mL (0.78-50 ng/mL) |
| Species Reactivity |
Human |
| Target |
Ficolin-1 |
| Cross Reactivity |
No significant cross-reactions have been observed between Human Ficolin-1 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
Short-term storage at 4°C and long-term storage at -20°C. |
Information
| Introduction |
Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
