This product is an ELISA kit for the in vitro determination of Human IL4 in the samples of Serum, plasma and other biological fluids. It is highly sensitive and available for the detection of Human IL4 as low as 7.8 pg/ml.
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| Assay Type | Sandwich ELISA |
| Sensitivity | 7.8 pg/ml (31.25-2000 pg/ml) |
| Species Reactivity | Human |
| Target | IL-4 |
| Cross Reactivity | No significant cross-reactions have been observed between Human IL4 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | Short-term storage at 4°C and long-term storage at -20°C. |
| Introduction | Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. |