Human MASP1 ELISA Kit-CTK-772(Cat#: CTK-772)
This product is an ELISA kit for the determination of Human Mannan-Binding Lectin serine Peptidase 1 (MASP1) in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Human MASP1 as low as 38.62 pg/mL.
Summary
Related Products & Services
Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
38.62 pg/mL (93.75-6000 pg/mL) |
| Pack Size |
96 tests |
| Species Reactivity |
Human |
| Target |
MASP1 |
| Cross Reactivity |
No significant cross-reactions have been observed between Human MASP1 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
4°C |
Information
| Introduction |
Mannan-binding lectin serine protease 1 functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
