Mouse Anti-Bovine Vitronectin Monoclonal Antibody (CTJS-229)(Cat#: CTA-190)

Name: Mouse Anti-Bovine Vitronectin Monoclonal Antibody (CTJS-229)
SKU: CTA-190
Rating: 5 (1 reviews)

This product is an unconjugated anti-Bovine Vitronectin Monoclonal antibody (CTJS-229) generated from the Mouse. The antibody can be used for ELISA; IHC.

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Specifications

Clonality	Monoclonal
Clone	CTJS-229
Host Animal	Mouse
Isotype	IgG1 Kappa
Immunogen	Lysed bovine corneal endothelial cells and extracellular matrix
Species Reactivity	Bovine; Equine; Rabbit
Applications	ELISA; IHC
Application Notes	ELISA: 1:100-1:2000 IHC: 1:10-1:500 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Bovine, Equine, Rabbit Vitronectin.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	50; 250 µg
Storage	Store at 4°C. Do not freeze.
Type	Primary Antibody

Target

Target Name	Vitronectin
Alternative Names	Serum Spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; VN; Vitronectin (Serum Spreading Factor, Somatomedin B, Complement S-Protein); Serum-Spreading Factor; Epibolin; VNT
Gene ID	7448
UniProt ID	P04004

Information

Introduction

Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is abundantly found in serum, the extracellular matrix and bone.In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading. It also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpins (serine protease inhibitors). It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.