This product is an iFluor® 647 conjugated anti-Human Complement C1QB Monoclonal antibody (TJL-11) generated from the Mouse. The antibody can be used for IHC, IHC-P.
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| Clonality | Monoclonal |
| Clone | TJL-11 |
| Host Animal | Mouse |
| Isotype | IgG1 Kappa |
| Immunogen | Recombinant fragment (aa 41-188) of Human C1QB protein |
| Species Reactivity | Human |
| Applications | IHC; IHC-P |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Complement C1QB. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | iFluor® 647 |
| Format | Liquid |
| Size | 0.1 ml |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | C1QB |
| Alternative Names | Complement C1q B Chain; Complement Component 1, Q Subcomponent, Beta Polypeptide; Complement Component 1, Q Subcomponent, B Chain; Complement C1q Subcomponent Subunit B; Complement C1q Chain B; Complement Subcomponent C1q Chain B; Complement Component C1q, B Chain; C1QB |
| Gene ID | 713 |
| UniProt ID | P02746 |
| Introduction | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |