Mouse Anti-Human C1QBP Monoclonal Antibody (TJL-25)(Cat#: CTMM-0322-JL133)
This product is an unconjugated anti-Human Complement C1QBP Monoclonal antibody (TJL-25) generated from the Mouse. The antibody can be used for ICC/IF, Flow.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
TJL-25 |
| Host Animal |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Recombinant Human C1QBP protein |
| Species Reactivity |
Human |
| Applications |
ICC/IF; Flow |
| Application Notes |
Flow: 1:25-1:100
ICC/IF: 1:20-1:100 |
| Specificity |
This antibody reacts with Human Complement C1QBP. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Liquid |
| Size |
100 µL |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
Target
| Target Name |
C1QBP |
| Alternative Names |
Complement C1q Binding Protein; Hyaluronan-Binding Protein 1; Complement Component 1 Q Subcomponent-Binding Protein, Mitochondrial; Complement Component 1, Q Subcomponent Binding Protein; Splicing Factor SF2-Associated Protein; C1q Globular Domain-Binding Protein; Mitochondrial Matrix Protein P32; ASF/SF2-Associated Protein P32; Glycoprotein GC1qBP; GC1QBP; GC1Q-R; HABP1 ; GC1q-R Protein; COXPD33; SF2P32; C1QBP; C1qBP |
| Gene ID |
708 |
| UniProt ID |
Q07021 |
Information
| Introduction |
The human complement subcomponent C1q associates with C1r and C1s in
order to yield the first component of the serum complement system (SCS).
The SCS contains over 30 glycoproteins that influence physiological mechanisms of the body in response to immune complex (the classical pathway),
carbohydRate (the lectin pathway) or bacterial (alternative pathway) initiation.
C1q binding protein (C1QBP), also designated gC1q-R, p32 (p33) or HABP1
(hyaluronan-binding protein 1), is known to bind the globular heads of C1q
molecules and inhibit C1 activation. C1QBP has been described as a complement receptor for C1q on B cells, neutrophils and mast cells. The C1QBP
protein may form homodimers. C1QBP is expressed in vascular endothelial
cells and has been found to be a multifunctional protein interacting with
elements of complement, coagulation and kinin systems. In addition, C1QBP
is a subunit of pre-mRNA splicing factor SF2/ASF. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
