Mouse Anti-Human C4BPA Monoclonal Antibody (TJL-47)(Cat#: CTMM-0322-JL212)
This product is an unconjugated anti-Human Complement C4BPA Monoclonal antibody (TJL-47) generated from the Mouse. The antibody can be used for Flow, ELISA.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
TJL-47 |
| Host Animal |
Mouse |
| Isotype |
IgG2b |
| Immunogen |
Native Human C4 binding protein |
| Species Reactivity |
Human |
| Applications |
Flow; ELISA |
| Application Notes |
Flow: 1-3 µg/mL
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Complement C4BPA. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Liquid |
| Size |
100 µg |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
Target
| Target Name |
C4BPA |
| Alternative Names |
C4b binding protein alpha chain; C4b-binding protein alpha chain; C4BP; complement component 4 binding protein alpha chain; complement component 4 binding protein alpha; complement component 4-binding protein alpha; Proline-rich protein; PRP |
| Gene ID |
722 |
| UniProt ID |
P04003 |
Information
| Introduction |
C4b-binding protein alpha chain is encoded by the human C4BPA gene. It controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also acceleRates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
