This product is a conjugated anti-Human Complement C4BPB Monoclonal antibody (CTJS-385) generated from the Mouse. The antibody can be used for WB, IF, IHC, FC.
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| Clonality | Monoclonal |
| Clone | CTJS-385 |
| Host Animal | Mouse |
| Isotype | IgG2b κ |
| Immunogen | Recombinant human C4BPB, a.a. 82-252 |
| Species Reactivity | Human |
| Applications | WB; IF; IHC; FC |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Complement C4BPB. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | iFluor® 594 |
| Format | Liquid |
| Size | 200 µg |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | C4BPB |
| Alternative Names | Complement Component 4 Binding Protein Beta; C4b-Binding Protein Beta Chain; Complement Component 4 Binding Protein, Beta Chain; Complement Component 4-Binding Protein, Beta; C4b Binding Protein, Beta Chain; C4BPB; C4BP |
| Gene ID | 725 |
| UniProt ID | P20851 |
| Introduction | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. |