Mouse Anti-Human C5b-9 Monoclonal Antibody (CTJS-605)(Cat#: CTA-012)
This product is an unconjugated anti-Human Complement C5b-9 Monoclonal antibody (CTJS-605) generated from the Mouse. The antibody can be used for ELISA; IF; IHC; WB.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-605 |
| Host Animal |
Mouse |
| Isotype |
IgG2aκ |
| Immunogen |
Purified human complement component C5b-9 |
| Species Reactivity |
Human; Baboon; Horse; Porcine |
| Applications |
ELISA; IF; IHC; WB |
| Application Notes |
ELISA: 1:100-1:2000
IHC: 1:10-1:500
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human, Baboon, Horse, Porcine both membrane-bound MAC and fluid phase SC5b-9 complexes. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
25; 100 µg |
| Storage |
4°C, store in dark |
| Type |
Primary Antibody |
Target
| Target Name |
C5b-9 complex |
| Alternative Names |
Membrane attack complex; MAC; Terminal complement complex; TCC; scC5b-9 |
Information
| Introduction |
C5b-9 complex is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. It is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is an effector of the immune system. Assembly of the MAC leads to pores that disrupt the cell membrane of target cells, leading to cell lysis and death. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
