Mouse Anti-Human C5b-9 Monoclonal Antibody (CTJS-652)(Cat#: CTA-1103)
This product is a human anti-CFB recombinant antibody and has a Neutralizing capacity of C5b-9. This antibody is available for C5b-9 Neutralization test and in human serum the IC50 is 4.715 nM.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-652 |
| Host Animal |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Recombinant Human CFB expressed in E.coli. |
| Species Reactivity |
Human |
| Applications |
Neut |
| Application Notes |
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Complement C5b-9. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Liquid |
| Size |
100 µg |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
| ProAb |
NeutAb |
Target
| Target Name |
C5b-9 complex |
| Alternative Names |
Membrane attack complex; MAC; Terminal complement complex; TCC; scC5b-9 |
Information
| Introduction |
C5b-9 complex is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. It is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is an effector of the immune system. Assembly of the MAC leads to pores that disrupt the cell membrane of target cells, leading to cell lysis and death. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
