Mouse Anti-Human CD46 Monoclonal Antibody (CTJS-78)(Cat#: CTA-249)
This product is an unconjugated anti-Human Complement CD46 Monoclonal antibody (CTJS-78) generated from the Mouse. The antibody can be used for FC; IF.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-78 |
| Host Animal |
Mouse |
| Isotype |
IgG2a Kappa |
| Immunogen |
Stimulated human leukocytes |
| Species Reactivity |
Human; Baboon |
| Applications |
FC; IF |
| Application Notes |
FC: 0.5 - 1 ug/10^6 cells
IF: 0.5 - 1.0 µg/mL
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human, Baboon CD46. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
20; 100 µg |
| Storage |
4°C |
| Type |
Primary Antibody |
Target
| Target Name |
CD46 |
| Alternative Names |
AHUS2; CD46 antigen; CD46 molecule complement regulatory protein; CD46; MCP; membrane cofactor protein (CD46; trophoblast-lymphocyte cross-reactive antigen); MIC10; TLXcomplement regulatory protein; Trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen |
| Gene ID |
4179 |
| UniProt ID |
P15529 |
Information
| Introduction |
CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. CD46 is an inhibitory complement receptor. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation (through cleavage) of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. The protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
