Mouse Anti-Human CD59 Monoclonal Antibody (CTJS-154)(Cat#: CTA-713)

Name: Mouse Anti-Human CD59 Monoclonal Antibody (CTJS-154)
SKU: CTA-713
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human MAC-inhibitory protein (CD59) Monoclonal antibody (CTJS-154) generated from the Mouse. The antibody can be used for WB, IP, IF, IHC, ELISA.

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Specifications

Clonality	Monoclonal
Clone	CTJS-154
Host Animal	Mouse
Isotype	IgG1 κ
Immunogen	Recombinant human CD59, a.a. 26-110
Species Reactivity	Human; Mouse; rat
Applications	WB; IP; IF; IHC; ELISA
Application Notes	WB: 1:100-1:1000 IF: 1:50-1:500 IHC: 1:50-1:500 ELISA: 1:30-1:3000 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human, Mouse, and Rat MAC-inhibitory protein (CD59).
Purity	≥95% as determined by SDS-PAGE
Conjugation	Unconjugated
Format	Liquid
Size	200 µg
Storage	Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle.
Type	Primary Antibody

Target

Target Name	CD59
Alternative Names	CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin
Gene ID	966
UniProt ID	P13987

Information

Introduction

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.