Mouse Anti-Human CD59 Monoclonal Antibody (CTJS-540) [Biotin](Cat#: CTA-699)
This product is a conjugated anti-Human MAC-inhibitory protein (CD59) Monoclonal antibody (CTJS-540) generated from the Mouse. The antibody can be used for FC, IHC, IP.
Summary
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Specifications
Clonality |
Monoclonal |
Clone |
CTJS-540 |
Host Animal |
Mouse |
Isotype |
IgG2a |
Immunogen |
Thymocytes and T lymphocytes |
Species Reactivity |
Human |
Applications |
FC; IHC; IP |
Application Notes |
The optimal working dilutions should be determined by the end user. |
Specificity |
This antibody reacts with Human MAC-inhibitory protein (CD59). |
Purity |
≥95% as determined by SDS-PAGE |
Conjugation |
Biotin |
Format |
Liquid |
Size |
100 µg |
Storage |
Store in dark at 4°C. Do Not Freeze. |
Type |
Primary Antibody |
Target
Target Name |
CD59 |
Alternative Names |
CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin |
Gene ID |
966 |
UniProt ID |
P13987 |
Information
Introduction |
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.